There's still 7 days left until the official release of New Super Mario Bros for Wii, but the game has been floating around the Internet since yesterday. It seems Nintendo decided to add their new copy protection to one of the most anticipated games for the Wii, New Super Mario Bros. From what I've read, no one using the USB Loaders can get it working. There are some with Wiikey v1 that says its working for them.

UPDATE: Using the Alt Dol method to boot New Super Mario Bros from your USB harddrive with Configurable USB Loader

1) download the hacked dol: http://www.mediafire.com/?ekmmzzgyyag
2) Extract it, you should have a file named "main.dol"
3) Rename "main.dol" to "SMNP.dol"
note: Rename "main.dol" to "SMNP01.dol" if you're using something other than Configurable USB Loader.
4) Copy "SMNP.dol" (or "SMNP01.dol" if not using Configurable USB Loader ) to the /usb-loader directory on your SD card
5) Put SD card back in Wii
6) Select your game and push 1 to enter the options screen
7) Go to the "Alternative dol" and select SD with the D-pad
8) Press 2 to save your options so that you don't have to do this everytime.

The game should now boot...

If it doesn't boot and you've given up.. buy the game. :) New Super Mario Bros